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RESEARCH TECHNICIAN II

Duke Clinical Research Institute
United States, North Carolina, Durham
300 West Morgan Street (Show on map)
Feb 04, 2026
School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,500 faculty physicians and researchers, more than 1,300 students, and more than 6,000 staff, the Duke University School of Medicine along with the Duke University School of Nursing, Duke University Health System and the Private Diagnostic Clinic (PDC) comprise Duke Health. a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.

We are seeking a motivated and detail-oriented Research Technician to join our research lab focused on the human fungal pathogen, Cryptococcus neoformans. The successful candidate will support ongoing research projects that involved molecular genetics, cell biology, and functional genomics. This person will assist with yeast strains preservation and organization and in day-to-day lab operations. Our laboratory is a team-based and therefore the candidate must be able to work both independently, but also as part of the team. Animal work is required.

Key Responsibilities



  • Culture, maintain, and genetically manipulate Cryptococcus strains
  • Perform standard molecular biology techniques, including PCR, DNA/RNA extraction, gel electrophoresis, and plasmid construction
  • Carry out yeast transformations, growth assays, and phenotypic characterizations
  • Maintain detailed and accurate records of experimental procedures and results
  • Assist in lab maintenance, including inventory management, solution preparation, and equipment upkeep
  • Contribute to data analysis and help prepare figures for presentations or publications
  • Participate in lab meetings and collaborate with other lab members
  • Assist key lab safety person with compliance of the institutional safety and regulatory policies


Qualifications

Required:



  • Bachelor's degree in Genetics, Biology, Biochemistry, or related field
  • Prior hands-on experience with molecular biology and genetic techniques
  • Strong organizational and communication skills
  • Ability to work independently and as part of a team
  • Be willing to handle animals


Preferred:



  • Previous experience working with yeast and mice
  • Familiarity with sterile technique and microbiology practices
  • Experience with software tools for data analysis (e.g., Excel, ImageJ, SnapGene)


What We Offer



  • Collaborative and supportive research environment
  • Opportunities for skill development and training
  • Potential for co-authorship on scientific publications
  • Access to university/institutional benefits (if applicable)


Application Instructions:
Please submit a cover letter, CV/resume, and contact information for 2-3 references to [application email or portal].


Duke is an Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex (including pregnancy and pregnancy related conditions), sexual orientation or military status.



Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas-an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.


Essential Physical Job Functions:

Certain jobs at Duke University and Duke University Health System may include essential job functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.


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