Research Scientist II

Position Description:

Every day, in ways both big and small, the Medical College of Wisconsin (MCW) is impacting lives for the better. MCW ... changemaking for a healthier Wisconsin. In the role of a Research Scientist II you will be working in Obstetrics and Gynecology.

Summary

The position offers the role of a senior non-faculty researcher exciting opportunity to work in a multidisciplinary environment at the intersection of molecular biology, nanomedicine, and translational cancer research.

Primary Responsibilities

• Design and conduct experiments on RNA interference (RNAi) and gene silencing in cell and animal models.
• Develop and optimize siRNA formulations and encapsulation strategies in lipid- or nanoparticle-based delivery systems.
• Perform in vivo testing of siRNA-loaded nanoliposomes in disease models to evaluate biodistribution, target gene knockdown, and therapeutic efficacy.
• Analyze and interpret molecular, biochemical, and imaging data.
• Collaborate with interdisciplinary teams including molecular biologists, chemists, and pharmacologists.

• Oversee assignments to researchers, biostatisticians, data analysts, and other members of the research team including staff members, who gather, code, enter and track data.
• Review research methodologies; plan, develop and compose protocols for implementation, assessment, testing, cost effectiveness, and quality.
• Supervise staff including hiring, training, performance reviews, coaching and corrective actions; oversee daily operations of the laboratory.
• Train students, residents and post-doctoral fellows in specific research protocols; develop training materials.
• Develop, implement and maintain a computerized record system for reporting results.
• Perform other duties as assigned.
• Prepare manuscripts, reports, and presentations; contribute to grant applications.

Knowledge - Skills - Abilities

• Knowledge of biology, chemistry, mathematics, documentation, and records management
• Proven expertise in RNA interference, siRNA design, and gene silencing techniques.
• Hands-on experience in nanoparticle or liposome-based drug delivery systems.
• Experience with in vivo models (mouse handling, injections, and tissue analysis).
• Experience in lipid nanoparticle (LNP) formulation, microfluidic encapsulation, or targeted delivery strategies.
• Knowledge of in vivo imaging techniques and pharmacokinetic analysis.
• Background in cancer biology or RNA therapeutics development.
• Strong publication record and ability to work independently and collaboratively.
• Data utilization, complex problem solving, critical thinking, resource management, and writing skills.

Preferred Schedule:



Between 7am to 5pm

Position Requirements:

Minimum Required Education: PhD in Molecular Biology, Biochemistry, Pharmacology, Biomedical
Engineering, Pharmacy or a related field.

Minimum Required Experience: 4 years

Preferred Education: Postdoctoral

Preferred Experience: 1-2 years

Why MCW?

• Outstanding Healthcare Coverage, including but not limited to Health, Vision, and Dental. Along with Flexible Spending options
• 403B Retirement Package
• Competitive Vacation and Paid Holidays offered
• Tuition Reimbursement
• Paid Parental Leave
• Pet Insurance
• On campus Fitness Facility, offering onsite classes.
• Additional discounted rates on items such as: Select cell phone plans, local fitness facilities, Milwaukee recreation and entertainment etc.

For a full list of positions see: www.mcw.edu/careers

For a brief overview of our benefits see: https://www.mcw.edu/departments/human-resources/benefits

At MCW all of our endeavors, from our internal operations to our interactions with our partners, are driven by our shared organizational values: Caring - Collaborative - Curiosity - Inclusive - Integrity - Respect. We are committed to fostering an inclusive environment that values diversity in backgrounds, experiences, and perspectives through merit-based processes and in alignment with all applicable laws. We believe that embracing human differences is critical to realize our vision of a healthier world, and we recognize that a healthy and thriving community starts from within. Our values define who we are, what we stand for and how we conduct ourselves at MCW. If you believe in embracing individuality and working together according to these principles to improve health for all, then MCW is the place for you.

MCW as an Equal Opportunity Employer and Commitment to Non-Discrimination


The Medical College of Wisconsin (MCW) is an Equal Opportunity Employer. We are committed to fostering an inclusive community of outstanding faculty, staff, and students, as well as ensuring equal educational opportunity, employment, and access to services, programs, and activities, without regard to an individual's race, color, national origin, religion, age, disability, sex, gender identity/expression, sexual orientation, marital status, pregnancy, predisposing genetic characteristic, or military status. Employees, students, applicants, or other members of the MCW community (including but not limited to vendors, visitors, and guests) may not be subjected to harassment that is prohibited by law or treated adversely or retaliated against based upon a protected characteristic.

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