Project Management Senior Manager, CMC Development and Manufacturing (Boston, MA)

Job Description

Vertex Pharmaceuticals is seeking aSenior Manager, Project Managementto join the Project Management Office (PMO) within the Biopharmaceutical Sciences Cell and Gene Therapy (CGT) organization. This role is critical in enabling effective, data-driven project execution through the development, implementation, and continuous improvement of project management tools, templates, dashboards, and reporting systems.

The successful candidate will play a key role in enhancing visibility into project scope, timelines, budgets, resources, and risks across the portfolio-enabling more informed and nimble decisions, optimizing project execution, and improving efficiency across multi-disciplinary teams. With a digital and analytical mindset, the ideal candidate will leverage technology and take a data-centric approach to optimizing project management solutions. This position will report directly to the Senior Director, Head of the Project Management Office.

Key Responsibilities

• Lead thedesign, development, deployment and continuous improvement of PMO tools and reporting systems to support cross-functional project execution in CGT development and manufacturing.

• Develop and refinestandardized processes, templates, and dashboardsto improve visibility into project scope, timelines, costs, resource allocation, and risk management.

• Lead the development of dashboards and self-service tools that empower teams to explore, analyze, and act on data.

• Partner with project managers, program leads, and functional leads todrive adoptionof new tools and consistent project management approaches across the CGT organization.

• Translate project execution data intoactionable insights and forecast projections, supporting timeline optimization and resource planning at both project and portfolio levels.

• Identify and implement integrated, digital and AI-driven toolsto increase the efficiency and impact of project management systems.

• Monitor the effectiveness of new tools/processes and leadcontinuous improvement cyclesbased on stakeholder feedback and evolving needs.

• Introduce new digital tools to simplify and integrate data across the portfolio and make recommendations for new ways to enhance/optimize existing project management software solutions

Qualifications

• Bachelor's degree in a scientific or business-related discipline required.

• Minimum of5 years of project management experiencein the pharmaceutical, biotech, or biologics industry.

• Demonstrated understanding ofCMC development and manufacturing processespreferred.

• Experience developing and implementingproject reporting tools, dashboards, or digital PM systemsin a complex, matrixed organization.

• Proficient in project management platforms (e.g., Smartsheet, MS Project, Planisware) and data visualization tools (e.g., Tableau, Power BI).

• Comfort with exploring and integratingdigital or AI technologiesinto project planning and reporting workflows.

• Strong organizational, analytical, and communication skills, with the ability to manage multiple priorities and influence across functional lines.

• Ability to work both strategically and tactically, independently and collaboratively, in a fast-paced, dynamic environment.

• PMP certification or advanced project management training a plus.

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Pay Range:

Disclosure Statement:

Flex Designation:

Flex Eligibility Status:

In this Hybrid-Eligible role, you can choose to be designated as:
1. Hybrid: work remotely up to two days per week; or select
2. On-Site: work five days per week on-site with ad hoc flexibility.

Note: The Flex status for this position is subject to Vertex's Policy on Flex @ Vertex Program and may be changed at any time.

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com