Investigator, In Vitro Biology (Oncology)

The Intracellular Targeted Cancer Therapeutics (ITCT) Biology Unit within the Oncology Research Unit is seeking an experienced Cancer Biologist for an Investigator role that will support a growing portfolio of precision oncology assets. The successful candidate will have a background in cancer biology with experience designing and executing biological studies to understand the mechanism of action small molecule cancer therapeutics.

Responsibilities:

• Work within a dynamic and global matrix team environment providing basic and translational biology support for target validation, drug discovery, and early clinical development of novel small molecule cancer therapies.

• Work independently to design, execute, and/or oversee impactful in vitro experiments informing the development of portfolio assets.

• Champion innovative experimental techniques or technologies, including medium-throughput scalable assay development, target-specific mechanistic biology, and monotherapy and combination anti-cancer efficacy testing of assets.

• Build communication networks across the Oncology Research Unit and broader organization.

• Guide the maturation and de-risking of novel therapeutic concepts.

Basic Qualifications:

• Ph.D. in Cell, Molecular, or Cancer Biology, Pharmacology, or a related life sciences field with 2+ years of post-doctoral research experience, or an M.S. with 3+ years of industry experience.

• Experience in designing, executing, and analyzing cellular and molecular biology experiments using small molecular therapeutics and a diverse array of current scientific techniques.

• Experience managing multiple projects in a matrix environment

Preferred Qualifications:

• Cancer drug discovery experience.

• Proven track record of scientific expertise and achievement in cell biology and cancer biology through peer-reviewed publications.

• Experience with functional testing of diverse small molecules.

• Experience in the design and implementation of functional genomic and/or chemogenomic screens and their application to drug discovery and/or target identification.

• Deep knowledge of tumor intrinsic disease mechanisms and resistance to cancer therapies.

• Working knowledge of -omic methods (e.g., sequencing, transcriptomics, and/or proteomics) and databases (e.g., Sanger, CCLE, DepMap, etc.).

• Excellent written and verbal communication skills.

• Attention to detail and proficient reasoning skills in experimental design, data analysis, statistical methods, and interpretation.

• Independence, problem-solving abilities, self-motivation, resourcefulness, and organizational, interpersonal, and communication skills.

• Ability to work efficiently in a fast-paced team environment

The position is available in Upper Providence, PA, USA.

#LI-GSK

Please visit GSK US Benefits Summary to learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it's also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US).

GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.